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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FENOFIBRIC ACID (is an active metabolite)
| FENOFIBRIC ACID CHOLINE FENOFIBRATE |
CARDIOVASCULAR | ORAL | Tmax 5 HOUR F 81 PERCENT PPB 99 PERCENT HT 20 HOUR SOLUBILITY INSOLUBLE IN WATER | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA PDB 7BQ0 (X-RAY STRUCTURE OF HUMAN PPARALPHA LIGAND BINDING DOMAIN-FENOFIBRIC ACID-SRC1 COACTIVATOR PEPTIDE CO-CRYSTALS OBTAINED BY DELIPIDATION AND CO-CRYSTALLIZATION) LIGAND CODE = F5A (link to the list of PDB complexes) Download experimental 3D coordinates of F5A with added hydrogens | Peroxisome proliferator-activated receptor alpha UNIPROT Q07869 PPARA more at DrugCentral | EMA | |||
