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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DALFAMPRIDINE
| DALFAMPRIDINE | NERVOUS SYSTEM | ORAL | Cmax 0.318 MICROMOLAR (10 MILLIGRAM) F 96 PERCENT VD 169 LITER (65 KILOGRAM) PPB 98 PERCENT Cl 20 LITER / HOUR (EQN) HT 5.8 HOUR SOLUBILITY SOLUBLE IN WATER | SHAKER KCNA | Voltage-gated potassium channel UNIPROT O43525 KCNQ3 more at DrugCentral | EMA | |||
