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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LODOXAMIDE
| LODOXAMIDE | SENSORY | OPHTHALMIC | HT 8.5 HOUR SOLUBILITY SOLUBLE IN WATER | G PROTEIN-COUPLED RECEPTOR GPR35 (PMID24113750) PDB 8H8J (LODOXAMIDE-BOUND GPR35 IN COMPLEX WITH G13) LIGAND CODE = WYB (link to the list of PDB complexes) Download experimental 3D coordinates of WYB with added hydrogens | G-protein coupled receptor 35 UNIPROT Q9HC97 GPR35 more at DrugCentral | EMA | |||
