Cheminformatic Tools and Databases for Pharmacology

session 51962 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ACRIVASTINE DISCONTINUED

ACRIVASTINE


ATC R06AX18

RESPIRATORY
ANTIHISTAMINE
HISTAMINE H1-RECEPTOR ANTAGONIST
TREATMENT OF CHRONIC URTICARIA AND ALLERGIC RHINITIS

ORAL

Cmax 652 NANOMOLAR

Tmax 1.14 HOUR

VD 29.9 LITER (65 KILOGRAM)

PPB 50 PERCENT

Cl 11.3 LITER / HOUR (65 KILOGRAM)

HT 1.9 HOUR

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

HISTAMINE H1-RECEPTOR (PMID1715267)

Histamine H1 receptor UNIPROT P35367 HRH1

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |