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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ABAMETAPIR DISCONTINUED
| ABAMETAPIR | ANTIPARASITIC | TOPICAL | Cmax 222 NANOMOLAR Tmax 1.05 HOUR PPB 91.8 PERCENT HT 21 HOUR | METALLOPROTEINASE PDB 5ARC (COOPERATIVE BIO-METALLIC SELECTIVITY IN A TAILORED PROTEASE ENABLES CREATION OF A C-C CROSS-COUPLING HECKASE) LIGAND CODE = EL3 (link to the list of PDB complexes) Download experimental 3D coordinates of EL3 with added hydrogens | Unknown more at DrugCentral | EMA | |||
