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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TOBRAMYCIN
| TOBRAMYCIN | NATURAL MOLECULE (link) ANTIINFECTIVES | INJECTION OPHTHALMIC INHALATION | VD 14.9 LITER (65 KILOGRAM) PPB 0 PERCENT Cl 6.24 LITER / HOUR (65 KILOGRAM) HT 2 HOUR SOLUBILITY SOLUBLE IN WATER | 30S RIBOSOMAL PROTEIN S12 16S RRNA PDB 4LFC (CRYSTAL STRUCTURE OF 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS) LIGAND CODE = TOY (link to the list of PDB complexes) Download experimental 3D coordinates of TOY with added hydrogens | Unknown more at DrugCentral | EMA | |||
