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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| SOLIFENACIN
| SOLIFENACIN | GENITO | ORAL | Cmax 173.7 NANOMOLAR (10 MILLIGRAM) F 90 PERCENT VD 600 LITER PPB 98 PERCENT Cl 7.3 LITER / HOUR (EQN) HT 56.5 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | MUSCARINIC ACETYLCHOLINE RECEPTOR | Muscarinic acetylcholine receptor M2 UNIPROT P08172 CHRM2 -- Muscarinic acetylcholine receptor M3 UNIPROT P20309 CHRM3 more at DrugCentral | EMA | |||
