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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| GALANTAMINE
| GALANTAMINE | NATURAL MOLECULE (link) NERVOUS SYSTEM | ORAL | F 90 PERCENT VD 175 LITER PPB 18 PERCENT Cl 18 LITER / HOUR HT 7 HOUR SOLUBILITY SPARINGLY SOLUBLE IN WATER | CHOLINESTERASE PDB 1QTI (ACETYLCHOLINESTERASE (E.C.3.1.1.7)) LIGAND CODE = GNT (link to the list of PDB complexes) Download experimental 3D coordinates of GNT with added hydrogens | Acetylcholinesterase UNIPROT P22303 ACHE more at DrugCentral | EMA | |||
