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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
PHENYTOIN (is an active metabolite)

PHENYTOIN


ATC N03AB02
ATC N03AB52

NERVOUS SYSTEM
ANTIEPILEPTIC
ANTICONVULSANT

ORAL INJECTION

Tmax 1.5 HOUR

PPB 88 PERCENT

HT 22 HOUR

VOLTAGE-DEPENDENT SODIUM CHANNEL

Sodium channel protein type 5 subunit alpha UNIPROT Q14524 SCN5A -- Sodium channel protein type 1 subunit alpha UNIPROT P35498 SCN1A

more at DrugCentral

EMA

ANSM (in French)

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SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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