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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ROSIGLITAZONE
| ROSIGLITAZONE |
METABOLISM | ORAL | Cmax 1.67 MICROMOLAR F 99 PERCENT VD 17.6 LITER PPB 99.8 PERCENT Cl 3.03 LITER / HOUR HT 3.5 HOUR SOLUBILITY SOLUBLE IN A BUFFERED AQUEOUS SOLUTION WITH PH 5 OF 2.3 BUT DECREASES WITH INCREASING PH | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA | Peroxisome proliferator-activated receptor gamma UNIPROT P37231 PPARG more at DrugCentral | EMA | |||
