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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FROVATRIPTAN
| FROVATRIPTAN | NERVOUS SYSTEM | ORAL | F 25 PERCENT VD 234 LITER (65 KILOGRAM) PPB 15 PERCENT Cl 10.5 LITER / HOUR HT 26 HOUR SOLUBILITY SOLUBLE IN WATER | 5-HYDROXYTRYPTAMINE 1D RECEPTOR 5-HYDROXYTRYPTAMINE 1B RECEPTOR | 5-hydroxytryptamine receptor 1B UNIPROT P28222 HTR1B -- 5-hydroxytryptamine receptor 1D UNIPROT P28221 HTR1D more at DrugCentral | EMA | |||
