| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| RIZATRIPTAN
| RIZATRIPTAN | NERVOUS SYSTEM | ORAL | F 45 PERCENT VD 125 LITER PPB 14 PERCENT Cl 34.6 LITER / HOUR (EQN) HT 2.5 HOUR SOLUBILITY SOLUBLE IN WATER AT ABOUT 42 MILLIGRAM / MILLILITER | 5-HYDROXYTRYPTAMINE 1D RECEPTOR 5-HYDROXYTRYPTAMINE 1B MONOAMINE OXIDASE TYPE A (MAO-A) | 5-hydroxytryptamine receptor 1B UNIPROT P28222 HTR1B -- 5-hydroxytryptamine receptor 1D UNIPROT P28221 HTR1D more at DrugCentral | EMA | |||
