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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ROPIVACAINE
| ROPIVACAINE | NERVOUS SYSTEM | INJECTION | Cmax 6.9 MICROMOLAR VD 41 LITER PPB 94 PERCENT Cl 23 LITER / HOUR HT 4.2 HOUR SOLUBILITY 53.8 MILLIGRAM / MILLILITER | SODIUM CHANNEL | Sodium channel protein type 5 subunit alpha UNIPROT Q14524 SCN5A -- Sodium channel protein type 1 subunit alpha UNIPROT P35498 SCN1A more at DrugCentral | EMA | |||
