| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CYSTEAMINE
| CYSTEAMINE | METABOLISM | ORAL OPHTHALMIC | Cmax 33.7 MICROMOLAR VD 156 LITER PPB 52 PERCENT Cl 72 LITER / HOUR HT 1.5 HOUR (EQN) SOLUBILITY HIGHLY WATER SOLUBLE | PDB 4CG4 (CRYSTAL STRUCTURE OF THE CHS-B30.2 DOMAINS OF TRIM20) LIGAND CODE = DHL (link to the list of PDB complexes) Download experimental 3D coordinates of DHL with added hydrogens | Unknown more at DrugCentral | EMA | |||
