| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ROCURONIUM
| ROCURONIUM | MUSCULO-SKELETAL SYSTEM | INJECTION | VD 16.2 LITER (65 KILOGRAM) PPB 30 PERCENT Cl 16.2 LITER / HOUR (65 KILOGRAM) HT 1.4 HOUR SOLUBILITY PARTITION COEFFICIENT IN N-OCTANOL/WATER IS 0.5 AT 20 DEGREE CELSIUS. | MUSCARINIC ACETYLCHOLINE RECEPTOR M2 NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-2 PDB 8F2S (CRYO-EM STRUCTURE OF TORPEDO NICOTINIC ACETYLCHOLINE RECEPTOR IN COMPLEX WITH ROCURONIUM, PORE-BLOCKED STATE) LIGAND CODE = RBR (link to the list of PDB complexes) Download experimental 3D coordinates of RBR with added hydrogens | Acetylcholine receptor UNIPROT P02708 CHRNA1 more at DrugCentral | EMA | |||
