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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
GOSERELIN

GOSERELIN


ATC L02AE03

ANTINEOPLASTIC
PROSTATE CANCER (THERAPEUTIC)
GONADOTROPIN RELEASING HORMONE (GNRH) AGONIST
INHIBITS PITUITARY GONADOTROPIN SECRETION

IMPLANTATION

Cmax 2.23 NANOMOLAR

VD 20.3 LITER

PPB 27.3 PERCENT

Cl 9.78 LITER / HOUR

HT 1.4 HOUR (EQN)

SOLUBILITY SOLUBLE IN WATER

GONADOTROPIN-RELEASING HORMONE RECEPTOR

Gonadotropin-releasing hormone receptor UNIPROT P30968 GNRHR

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