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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DOXAZOSIN
| DOXAZOSIN | CARDIOVASCULAR | ORAL | Cmax 57 NANOMOLAR (8 MILLIGRAM) F 59 PERCENT VD 84.5 LITER (65 KILOGRAM) PPB 98 PERCENT Cl 6.24 LITER / HOUR (65 KILOGRAM) HT 17 HOUR | ALPHA-1 ADRENERGIC RECEPTOR | Alpha-1A adrenergic receptor UNIPROT P35348 ADRA1A -- Alpha-1D adrenergic receptor UNIPROT P25100 ADRA1D more at DrugCentral | EMA | |||
