Cheminformatic Tools and Databases for Pharmacology

session 60884 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
BENZTROPINE

BENZTROPINE


ATC N04AC01

NERVOUS SYSTEM
ANTIPARKINSONIAN
ANTIDYSKINETICS
MUSCARINIC ANTAGONISTS
DOPAMINE TRANSPORTER LIGANDS (PMID18786172)

ORAL INJECTION

SOLUBILITY SOLUBLE IN WATER

DOPAMINE TRANSPORTER
MUSCARINIC ACETYLCHOLINE RECEPTOR

PDB 6F6S (CRYSTAL STRUCTURE OF EBOLAVIRUS GLYCOPROTEIN IN COMPLEX WITH BENZTROPINE)

LIGAND CODE = CXQ (link to the list of PDB complexes)

Download experimental 3D coordinates of CXQ with added hydrogens

Muscarinic acetylcholine receptor M1 UNIPROT P11229 CHRM1

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |