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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
PHENTOLAMINE

PHENTOLAMINE


ATC C04AB01
ATC V03AB36

CARDIOVASCULAR
ALPHA ADRENERGIC RECEPTOR ANTAGONIST
ANTIHYPERTENSIVE AGENTS
SYMPATHOLYTICS
REVERSAL OF SOFT-TISSUE ANESTHESIA

INJECTION OPHTHALMIC

Tmax 0.25 HOUR

F 100 PERCENT

HT 2.5 HOUR

SOLUBILITY SPARINGLY SOLUBLE IN WATER

ALPHA ADRENERGIC RECEPTOR

Alpha-2A adrenergic receptor UNIPROT P08913 ADRA2A -- Alpha-1A adrenergic receptor UNIPROT P35348 ADRA1A

more at DrugCentral

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ANSM (in French)

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