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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| GREPAFLOXACIN DISCONTINUED
| GREPAFLOXACIN | ANTIBIOTIC | ORAL | Cmax 4.95 MICROMOLAR (400 MG - 600 MG) F 70 PERCENT VD 325 LITER (65 KILOGRAM) PPB 50 PERCENT Cl 15 LITER / HOUR (EQN) HT 15 HOUR SOLUBILITY SOLUBLE IN WATER | DNA TOPOISOMERASE II (DNA GYRASE) DNA TOPOISOMERASE IV | DNA topoisomerase 4 UNIPROT P72525 parC -- DNA gyrase UNIPROT P0A4L9 gyrB more at DrugCentral | EMA | |||
