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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| IPRATROPIUM
| IPRATROPIUM |
RESPIRATORY | INHALATION NASAL | Cmax NOT DETECTABLE F 3 PERCENT VD 0.43 LITER (EQN) PPB 9 PERCENT Cl 0.15 LITER / HOUR HT 2 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | MUSCARINIC RECEPTOR PDB 2X8M (CRYSTAL STRUCTURE OF CBPF IN COMPLEX WITH IPRATROPIUM BY SOAKING) LIGAND CODE = X8M (link to the list of PDB complexes) Download experimental 3D coordinates of X8M with added hydrogens | Muscarinic acetylcholine receptor M3 UNIPROT P20309 CHRM3 more at DrugCentral | EMA | |||
