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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
NIMODIPINE

NIMODIPINE


ATC C08CA06

CARDIOVASCULAR
VASODILATOR
CALCIUM CHANNEL ANTAGONIST
ANTIHYPERTENSIVE AGENTS

ORAL

Tmax 1 HOUR

F 13 PERCENT

VD 66 LITER

PPB 95 PERCENT

Cl 54 LITER / HOUR

HT 1.5 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

CALCIUM CHANNEL

Voltage-dependent L-type calcium channel subunit alpha-1C UNIPROT Q13936 CACNA1C -- Voltage-dependent L-type calcium channel subunit alpha-1D UNIPROT Q01668 CACNA1D

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