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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ECONAZOLE
| ECONAZOLE |
DERMATOLOGICALS | TOPICAL | Cmax 1 NANOMOLAR Tmax 6.8 HOUR | CYTOCHROME P450 PDB 6B5V (STRUCTURE OF TRPV5 IN COMPLEX WITH ECONAZOLE) LIGAND CODE = ECL (link to the list of PDB complexes) Download experimental 3D coordinates of ECL with added hydrogens | Lanosterol 14-alpha demethylase UNIPROT P10613 ERG11 more at DrugCentral | EMA | |||
