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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ATENOLOL
| ATENOLOL |
CARDIOVASCULAR | ORAL INJECTION | Tmax 3 HOUR F 50 PERCENT VD 61 LITER PPB 11 PERCENT Cl 9.75 LITER / HOUR HT 6.5 HOUR SOLUBILITY 26.5 MILLIGRAM / MILLILITER | BETA-1 ADRENERGIC RECEPTOR PDB 2NUV (CRYSTAL STRUCTURE OF THE COMPLEX OF C-TERMINAL LOBE OF BOVINE LACTOFERRIN WITH ATENOLOL AT 2.25 A RESOLUTION) LIGAND CODE = 2TN (link to the list of PDB complexes) Download experimental 3D coordinates of 2TN with added hydrogens | Beta-1 adrenergic receptor UNIPROT P08588 ADRB1 more at DrugCentral | EMA | |||
