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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| METHARBITAL DISCONTINUED
| METHARBITAL | NERVOUS SYSTEM | ORAL | GAMMA-AMINOBUTYRIC-ACID RECEPTOR PDB 5STF (PANDDA ANALYSIS GROUP DEPOSITION -- AAR2, RNASEH IN COMPLEX WITH FRAGMENT P02H02 FROM THE F2X-UNIVERSAL LIBRARY) LIGAND CODE = VOK (link to the list of PDB complexes) Download experimental 3D coordinates of VOK with added hydrogens | GABA-A receptor more at DrugCentral | EMA | ||||
