Cheminformatic Tools and Databases for Pharmacology

session 57167 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DOBUTAMINE

DOBUTAMINE


ATC C01CA07

CARDIOVASCULAR
CARDIOTONIC
ADRENERGIC BETA AGONISTS
SYMPATHOMIMETIC
CATECHOLAMINE

INJECTION

Cmax 332 NANOMOLAR

VD 13 LITER

Cl 249 LITER / HOUR

HT 0.033 HOUR

BETA-1 ADRENERGIC RECEPTOR
CATECHOL O-METHYLTRANSFERASE (COMT)

PDB 2Y00 (TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND PARTIAL AGONIST DOBUTAMINE (CRYSTAL DOB92))

LIGAND CODE = Y00 (link to the list of PDB complexes)

Download experimental 3D coordinates of Y00 with added hydrogens

Beta-1 adrenergic receptor UNIPROT P08588 ADRB1 -- Beta-2 adrenergic receptor UNIPROT P07550 ADRB2

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |