| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CODEINE
| CODEINE | NATURAL MOLECULE (link)
NERVOUS SYSTEM | ORAL | Cmax 662.2 NANOMOLAR Tmax 1 HOUR VD 292.5 LITER (65 KILOGRAM) PPB 16 PERCENT Cl 58.5 LITER / HOUR (65 KILOGRAM) HT 2.9 HOUR SOLUBILITY SOLUBLE IN WATER | OPIOID RECEPTOR | Mu-type opioid receptor UNIPROT P35372 OPRM1 more at DrugCentral | EMA | |||
