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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| THIORIDAZINE
| THIORIDAZINE | NERVOUS SYSTEM | ORAL | Cmax 0.55 MICROMOLAR HT 15 HOUR | DOPAMINE RECEPTOR 5-HYDROXYTRYPTAMINE 2A RECEPTOR ALPHA-1A ADRENERGIC RECEPTOR PDB 4I1R (HUMAN MALT1 (CASPASE-IG3) IN COMPLEX WITH THIORIDAZINE) LIGAND CODE = LZU (link to the list of PDB complexes) Download experimental 3D coordinates of LZU with added hydrogens | D(2) dopamine receptor UNIPROT P14416 DRD2 more at DrugCentral | EMA | |||
