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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DRONEDARONE
| DRONEDARONE | CARDIOVASCULAR | ORAL | F 15 PERCENT VD 1400 LITER PPB 98 PERCENT Cl 140 LITER / HOUR HT 16 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | IONIC CHANNELS | Potassium,sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 UNIPROT O60741 HCN1 -- Potassium,sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 UNIPROT Q9UL51 HCN2 more at DrugCentral | EMA | |||
