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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| STREPTOMYCIN
| STREPTOMYCIN |
METABOLISM | INJECTION | Cmax 75 MICROMOLAR F 84 PERCENT (INTRAMUSCULAR) VD 22 LITER (65 KILOGRAM) PPB 35 PERCENT Cl 3 LITER / HOUR HT 4 HOUR SOLUBILITY SOLUBLE IN WATER | RIBOSOMAL PROTEIN PDB 1NTA (2.9 A CRYSTAL STRUCTURE OF STREPTOMYCIN RNA-APTAMER) LIGAND CODE = SRY (link to the list of PDB complexes) Download experimental 3D coordinates of SRY with added hydrogens | Unknown more at DrugCentral | EMA | |||
