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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DALFOPRISTIN
| DALFOPRISTIN | ANTIINFECTIVES | INJECTION INTRAVENOUS | Cmax 11.5 MICROMOLAR VD 15.6 LITER PPB 18 PERCENT Cl 46.8 LITER / HOUR (65 KILOGRAM) HT 0.7 HOUR | VIRGINIAMYCIN ACETYLTRANSFERASE D (VATD) RIBOSOME PDB 4U26 (CRYSTAL STRUCTURE OF THE E. COLI RIBOSOME BOUND TO DALFOPRISTIN AND QUINUPRISTIN.) LIGAND CODE = DOL (link to the list of PDB complexes) Download experimental 3D coordinates of DOL with added hydrogens | Unknown more at DrugCentral | EMA | |||
