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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
QUINUPRISTIN

QUINUPRISTIN


ATC J01FG02

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
STREPTOGRAMINS
BACTERIAL RIBOSOME (INHIBITS THE LATE PHASE OF PROTEIN SYNTHESIS)

INJECTION INTRAVENOUS

Cmax 3.1 MICROMOLAR

VD 29 LITER (65 KILOGRAM)

PPB 66 PERCENT

Cl 46.8 LITER / HOUR (65 KILOGRAM)

HT 0.85 HOUR

RIBOSOME
STAPHYLOCOCCUS AUREUS VIRGINIAMYCIN B LYASE

PDB 2Z2P (CATALYTICALLY INACTIVE H270A VIRGINIAMYCIN B LYASE FROM STAPHYLOCOCCUS AUREUS)

Unknown

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