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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TAZOBACTAM
| TAZOBACTAM | ANTIINFECTIVES | INJECTION INTRAVENOUS | Cmax 113.3 MICROMOLAR Tmax 1 HOUR VD 18.2 LITER PPB 30 PERCENT Cl 12.3 LITER / HOUR HT 1.2 HOUR | PENICILLIN-BINDING PROTEIN PDB 1VM1 (STRUCTURE OF SHV-1 BETA-LACTAMASE INHIBITED BY TAZOBACTAM) LIGAND CODE = TAZ (link to the list of PDB complexes) Download experimental 3D coordinates of TAZ with added hydrogens | Beta-lactamase TEM UNIPROT P62593 bla more at DrugCentral | EMA | |||
