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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| AZITHROMYCIN
| AZITHROMYCIN |
ANTIINFECTIVES | ORAL INJECTION OPHTHALMIC | Cmax 1.33 MICROMOLAR F 34 PERCENT VD 2021 LITER (65 KILOGRAM) PPB 29 PERCENT Cl 37.8 LITER / HOUR HT 68 HOUR | 50S RIBOSOMAL PROTEIN PDB 5UXD (CRYSTAL STRUCTURE OF MACROLIDE 2'-PHOSPHOTRANSFERASE MPHH FROM BRACHYBACTERIUM FAECIUM IN COMPLEX WITH AZITHROMYCIN) LIGAND CODE = ZIT (link to the list of PDB complexes) Download experimental 3D coordinates of ZIT with added hydrogens | Unknown more at DrugCentral | EMA | |||
