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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| IDARUBICIN
| IDARUBICIN | ANTINEOPLASTIC | INJECTION | VD 2470 LITER (65 KILOGRAM) PPB 97 PERCENT Cl 93 LITER / HOUR (65 KILOGRAM) HT 22 HOUR | DNA TOPOISOMERASE 2-ALPHA PDB 4LB2 (X-RAY STUDY OF HUMAN SERUM ALBUMIN COMPLEXED WITH IDARUBICIN) LIGAND CODE = DM5 (link to the list of PDB complexes) Download experimental 3D coordinates of DM5 with added hydrogens | DNA topoisomerase 2-alpha UNIPROT P11388 TOP2A more at DrugCentral | EMA | |||
