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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
VANCOMYCIN

VANCOMYCIN


ATC A07AA09
ATC J01XA01
ATC S01AA28

ANTIINFECTIVES
MACROLIDE
GLYCOPEPTIDE ANTIBACTERIALS
ANTIBACTERIAL
ANTIBIOTIC
INHIBITION OF CELL-WALL BIOSYNTHESIS

ORAL INTRAVENOUS INJECTION

Cmax 0.45 MICROMOLAR

F POORLY ABSORBED

VD 35.1 LITER (65 KILOGRAM)

PPB 30 PERCENT

Cl 5.07 LITER / HOUR (65 KILOGRAM)

HT 6.5 HOUR

DNA

PDB 1PNV (TDP-EPI-VANCOSAMINYLTRANSFERASE GTFA FROM AMYCOLATOPSIS ORIENTALIS)

Unknown

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