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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| AZTREONAM
| AZTREONAM | ANTIINFECTIVES | INJECTION INHALATION | Cmax 1.5 MICROMOLAR VD 12.6 LITER PPB 60 PERCENT Cl 5.4 LITER / HOUR HT 1.7 HOUR | PENICILLIN-BINDING PROTEIN 3 BETA-LACTAMASE PDB 1FR6 (BETA-LACTAMASE FROM CITROBACTER FREUNDII) | Peptidoglycan synthase FtsI UNIPROT P0AD68 ftsI -- Penicillin-binding protein 1A UNIPROT P02918 mrcA more at DrugCentral | EMA | |||
