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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PIPERACILLIN
| PIPERACILLIN | ANTIINFECTIVES | INJECTION | Cmax 0.57 MILLIMOLAR Tmax 0.5 HOUR VD 17.5 LITER (65 KILOGRAM) PPB 16 PERCENT Cl 15.6 LITER / HOUR (65 KILOGRAM) HT 0.96 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | PENICILLIN-BINDING PROTEINS 1A/1B PDB 3Q07 (CTX-M-9 S70G IN COMPLEX WITH PIPERACILLIN) LIGAND CODE = WPP (link to the list of PDB complexes) Download experimental 3D coordinates of WPP with added hydrogens | Bacterial penicillin-binding protein UNIPROT P02918 mrcA more at DrugCentral | EMA | |||
