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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CEFACLOR
| CEFACLOR | ANTIINFECTIVES | ORAL | Cmax 62 MICROMOLAR (1 GRAM) Tmax 0.75 HOUR F 85 PERCENT PPB 37.5 PERCENT HT 0.75 HOUR | PENICILLIN-BINDING PROTEINS 1A/1B PDB 7Q4X (CRYSTAL STRUCTURE OF EQUINE SERUM ALBUMIN IN COMPLEX WITH CEFACLOR) LIGAND CODE = 8XI (link to the list of PDB complexes) Download experimental 3D coordinates of 8XI with added hydrogens | Bacterial penicillin-binding protein UNIPROT P02918 mrcA more at DrugCentral | EMA | |||
