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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CEFAZOLIN

CEFAZOLIN


ATC J01DB04

ANTIINFECTIVES
ANTIBACTERIAL
ANTIBIOTIC
CEPHALOSPORINS

INJECTION INTRAVENOUS

Cmax 407 MICROMOLAR (1 GRAM)

Tmax 0.25 HOUR (2 GRAM)

VD 7.8 LITER (65 KILOGRAM)

PPB 82 PERCENT

Cl 3.4 LITER / HOUR

HT 1.8 HOUR

PENICILLIN-BINDING PROTEINS 1A/1B

Bacterial penicillin-binding protein UNIPROT P02918 mrcA

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