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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
MITOMYCIN

MITOMYCINNATURAL MOLECULE (link)


NATURAL MOLECULE (link)


ATC L01DC03

ANTINEOPLASTIC
CROSS-LINKING REAGENTS
ALKYLATING AGENTS
INHIBITS THE SYNTHESIS OF DEOXYRIBONUCLEIC ACID (DNA)
CYTOTOXIC
ISOLATED FROM THE BROTH OF STREPTOMYCES VERTICILLUS YINGTANENSIS

INJECTION TOPICAL PYELOCALYCEAL

Cmax 7.1 MICROMOLAR (30 MILLIGRAM)

HT 0.76 HOUR

DNA

Unknown

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