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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| MINOCYCLINE
| MINOCYCLINE | NATURAL MOLECULE (link)
ANTIINFECTIVES | ORAL INJECTION DENTAL TOPICAL | Cmax 9.14 MICROMOLAR (200 MILLIGRAM) VD 104 LITER (65 KILOGRAM) Cl 4.68 LITER / HOUR (65 KILOGRAM) HT 19 HOUR | 30S RIBOSOMAL PROTEIN PDB 4A99 (STRUCTURE OF THE TETRACYCLINE DEGRADING MONOOXYGENASE TETX IN COMPLEX WITH MINOCYCLINE) LIGAND CODE = MIY (link to the list of PDB complexes) Download experimental 3D coordinates of MIY with added hydrogens | Unknown more at DrugCentral | EMA | |||
