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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
AMPHOTERICIN B

AMPHOTERICIN B


ATC J02AA01
ATC A01AB04
ATC A07AA07
ATC G01AA03

ANTIINFECTIVES
ANTIFUNGAL
AMEBICIDES
ANTI-BACTERIAL AGENTS
ANTIPROTOZOAL AGENTS
PRODUCED FROM A STRAIN OF STREPTOMYCES NODOSUS
HIGH AFFINITY FOR THE ERGOSTEROL COMPONENT OF THE FUNGAL CELL MEMBRANE

TOPICAL ORAL INJECTION

Cmax 89.9 MICROMOLAR

VD 6.5 LITER (65 KILOGRAM)

PPB 90 PERCENT

Cl 0.715 LITER / HOUR (65 KILOGRAM)

HT 8.5 HOUR

MEMBRANE

ERGOSTEROL CHELATING AGENT CHEMBL2364028 ERGOSTEROL CANDIDA ALBICANSANSM (in French)

Dailymed
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SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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