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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DEMECLOCYCLINE

DEMECLOCYCLINE


ATC J01AA01
ATC D06AA01

ANTIINFECTIVES
ANTIBACTERIAL
ANTIBIOTIC
TETRACYCLINES
PRODUCT BY STREPTOMYCES AUREOFACIENS

ORAL

Cmax 2.62 MICROMOLAR (150 MILLIGRAM)

VD 84.5 LITER (65 KILOGRAM)

PPB 65 PERCENT

Cl 4.3 LITER / HOUR (65 KILOGRAM)

HT 13 HOUR

30S RIBOSOMAL PROTEIN

BACTERIAL 70S RIBOSOME INHIBITOR CHEMBL2363135 BACTERIAL 70S RIBOSOME 16S RIBOSOMAL RNA BACTERIAANSM (in French)

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