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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PENICILLIN V
| PENICILLIN V | ANTIINFECTIVES | ORAL | VD 26.6 LITER (65 KILOGRAM) PPB 80 PERCENT Cl 26.5 LITER / HOUR (65 KILOGRAM) HT 0.84 HOUR | BETA-LACTAMASE PENICILLIN-BINDING PROTEINS 1A/1B PDB 2Z71 (STRUCTURE OF TRUNCATED MUTANT CYS1GLY OF PENICILLIN V ACYLASE FROM BACILLUS SPHAERICUS CO-CRYSTALLIZED WITH PENICILLIN V) LIGAND CODE = PNV (link to the list of PDB complexes) Download experimental 3D coordinates of PNV with added hydrogens | Bacterial penicillin-binding protein UNIPROT P02918 mrcA more at DrugCentral | EMA | |||
