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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| METHICILLIN DISCONTINUED
| METHICILLIN | ANTIINFECTIVES | INJECTION | VD 20.8 LITER (65 KILOGRAM) PPB 57 PERCENT Cl 25.7 LITER / HOUR (65 KILOGRAM) HT 0.64 HOUR | PENICILLIN-BINDING PROTEINS 1A/1B PDB 3KP4 (STAPHYLOCOCCUS EPIDERMIDIS TCAR IN COMPLEX WITH METHICILLIN) LIGAND CODE = MII (link to the list of PDB complexes) Download experimental 3D coordinates of MII with added hydrogens | Penicillin-binding protein UNIPROT P72355 pbp4 more at DrugCentral | EMA | |||
