Cheminformatic Tools and Databases for Pharmacology

session 21744 - Total of 2 hits - Display   hits per page:

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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
COLISTIMETHATE (has an active metabolite)

COLISTIMETHATE


ATC A07AA10
ATC J01XB01

ANTIINFECTIVES
ANTIBACTERIAL
GRAM-NEGATIVE BACILLI

INJECTION

VD 49.4 LITER (EQN)

Cl 13.7 LITER / HOUR (PMID19433570)

HT 2.5 HOUR

MEMBRANE

CELL MEMBRANE INHIBITOR CHEMBL2364031 CELL MEMBRANE BACTERIAANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank

2 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
COLISTIN (is an active metabolite)

COLISTIN


ATC J01XB01
ATC A07AA10

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
POLYMYXIN E
DISRUPTS THE BACTERIAL CELL MEMBRANE

ORAL OTIC

Cmax 1.99 MICROMOLAR (PMID19433570)

VD 189 LITER (PMID19433570)

Cl 13.7 LITER / HOUR (PMID19433570)

HT 14.4 HOUR (PMID19433570)

MEMBRANE

CELL OUTER MEMBRANE INHIBITOR CHEMBL2364032 CELL OUTER MEMBRANE BACTERIAANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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