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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DISULFIRAM

DISULFIRAM


ATC N07BB01
ATC P03AA04
ATC P03AA54

NERVOUS SYSTEM
BLOCKS THE OXIDATION OF ALCOHOL AND PROMOTES UNPLEASANT SYMPTOMS
TREATMENT OF CHRONIC ALCOHOL PATIENTS

ORAL

SOLUBILITY SOLUBLE IN WATER

ALCOHOL DEHYDROGENASE

ALDEHYDE DEHYDROGENASE INHIBITOR CHEMBL1935 ALDEHYDE DEHYDROGENASE P05091 ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL HOMO SAPIENS ENZYME REDUCTASEANSM (in French)

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