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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
TIGECYCLINE

TIGECYCLINE


ATC J01AA12

ANTIINFECTIVES
ANTIBACTERIAL
TETRACYCLINE

INTRAVENOUS

Cmax 1.48 MICROMOLAR (50 MILLIGRAM EVERY 12 HOUR)

VD 639 LITER

PPB 80 PERCENT

Cl 23.8 LITER / HOUR

HT 42.4 HOUR

30S RIBOSOMAL PROTEIN

BACTERIAL 70S RIBOSOME INHIBITOR CHEMBL2363135 BACTERIAL 70S RIBOSOME 16S RIBOSOMAL RNA BACTERIAANSM (in French)

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