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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ENTECAVIR (has an active metabolite)
| ENTECAVIR | ANTIINFECTIVES | ORAL | Cmax 29.6 NANOMOLAR (1 MILLIGRAM) Tmax 1 HOUR F 100 PERCENT VD 4596 LITER (EQN) PPB 13 PERCENT Cl 23 LITER / HOUR (RENAL ClEARANCE) HT 138.5 HOUR SOLUBILITY SLIGHTLY SOLUBLE IN WATER | HBV REVERSE TRANSCRIPTASE | Protein P UNIPROT Q9IF40 P more at DrugCentral | EMA | |||
